Epithalon (Epitalon)

$140.00

Epithalon (Epitalon) is a synthetic tetrapeptide derived from Epithalamin and widely studied in gerontology and genomic regulation research. It is best known for its reported ability to modulate telomerase activity, the enzyme involved in maintaining telomere integrity at the ends of chromosomes. In vitro studies in human somatic cells suggest Epithalon may increase telomerase activity and support telomere elongation, mechanisms associated with cellular longevity and reduced age-related genomic instability.

Beyond telomere biology, research indicates Epithalon may influence gene expression and circadian signaling pathways, including those tied to melatonin synthesis and immune regulation. These combined properties have made Epithalon a prominent research compound in models of aging, oxidative stress, and age-associated functional decline. Epithalon is supplied strictly for in-vitro laboratory research use and is not intended for human or animal application.

For research use only. Not for human consumption.

References:
Khavinson VK et al., Bull Exp Biol Med, 2003;135(4):429–432
Khavinson VK et al., Biogerontology, 2007;8(3):305–313
Anisimov VN et al., Neuro Endocrinol Lett, 2003;24(3–4):233–240

Category:

Description

Properties
Molecular Formula C14H22N4O9
Molecular Weight 390.35
Monoisotopic Mass 390.13867829
Polar Area 225
Complexity 607
XLogP -5.5
Heavy Atom Count 27
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 10
Rotatable Bond Count 12
PubChem LCSS Epitalon Laboratory Chemical Safety Summary
Identifiers
CID 219042
InChI InChI=1S/C14H22N4O9/c1-6(15)12(25)17-7(2-3-9(19)20)14(27)18-8(4-10(21)22)13(26)16-5-11(23)24/h6-8H,2-5,15H2,1H3,(H,16,26)(H,17,25)(H,18,27)(H,19,20)(H,21,22)(H,23,24)/t6-,7-,8-/m0/s1
InChIKey HGHOBRRUMWJWCU-FXQIFTODSA-N
Isometric SMILES C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)O)N
Canonical SMILES CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)O)N
IUPAC Name (4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

Reviews

There are no reviews yet.

Be the first to review “Epithalon (Epitalon)”

Your email address will not be published. Required fields are marked *