Decapeptide-12 200mg (Topical)

$65.00

Decapeptide-12 is a synthetic oligopeptide investigated for its inhibitory activity against tyrosinase, the copper-containing enzyme central to melanin synthesis. In laboratory and animal models, the peptide has demonstrated the ability to reduce melanin production through reversible interaction with tyrosinase, making it a subject of interest in pigmentation and dermatologic research.

Experimental studies evaluate Decapeptide-12 for its effects on melanocyte biology, pigment formation pathways, and oxidative enzymatic cascades involved in skin photodamage and hyperpigmentation models. All findings are derived from in-vitro, ex-vivo, or preclinical investigations and are intended strictly for scientific and research applications.

For research use only. Not for human consumption.

References:
Pillaiyar T et al., Med Res Rev, 2017 37(5):931–1015
Ando H et al., Pigment Cell Res, 2007 20(2):110–119
Solano F et al., Pigment Cell Melanoma Res, 2006 19(6):550–571

Category:

Description

Properties
Molecular Formula C65H90N18O17
Molecular Weight 1395.5
Monoisotopic Mass 1394.67313347
Polar Area 617
Complexity 2690
XLogP -6.5
Heavy Atom Count 100
Hydrogen Bond Donor Count 23
Hydrogen Bond Acceptor Count 21
Rotatable Bond Count 42
PubChem LCSS Decapeptide-12 Laboratory Chemical Safety Summary
Identifiers
CID 25087629
InChI InChI=1S/C65H90N18O17/c66-24-4-3-9-45(76-55(91)47(11-6-26-73-65(70)71)77-60(96)51(32-84)81-57(93)46(10-5-25-72-64(68)69)75-54(90)43(67)27-35-12-18-39(87)19-13-35)56(92)78-48(28-36-14-20-40(88)21-15-36)58(94)82-53(34-86)62(98)83-52(33-85)61(97)79-49(30-38-31-74-44-8-2-1-7-42(38)44)59(95)80-50(63(99)100)29-37-16-22-41(89)23-17-37/h1-2,7-8,12-23,31,43,45-53,74,84-89H,3-6,9-11,24-30,32-34,66-67H2,(H,75,90)(H,76,91)(H,77,96)(H,78,92)(H,79,97)(H,80,95)(H,81,93)(H,82,94)(H,83,98)(H,99,100)(H4,68,69,72)(H4,70,71,73)
InChIKey OYVFAMLECFSFEI-UHFFFAOYSA-N
Isometric SMILES C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NC(CC3=CC=C(C=C3)O)C(=O)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC5=CC=C(C=C5)O)N
Canonical SMILES C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NC(CC3=CC=C(C=C3)O)C(=O)O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(CO)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC5=CC=C(C=C5)O)N
IUPAC Name 2-[[2-[[2-[[2-[[2-[[6-amino-2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid

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