Description

Trichloroacetic Acid ACS Reagent, ≥99.0%, 100 Gram, Case/4

Synonym: TCA

CAS Number 76-03-9
Linear Formula Cl3CCOOH
Molecular Weight 163.39
Beilstein/REAXYS Number 970119
EC Number 200-927-2
MDL number MFCD00004177
PubChem Substance ID 24900373
NACRES NA.21

grade	ACS reagent
vapor density
vapor pressure	1 mmHg ( 51 °C)
assay	≥99.0%
impurities	Substances darkened by sulfuric acid, passes test
	≤0.01% insoluble matter
ign. residue	≤0.03%
refractive index	n20/D 1.62 (lit.)
bp	196 °C (lit.)
mp	54-58 °C (lit.)
solubility	H2O: 1 g/10 mL
density	1.62 g/mL at 25 °C (lit.)
anion traces	chloride (Cl-): ≤0.002%
	nitrate (NO3-): ≤0.002%
	phosphate (PO43-): ≤5 ppm
	sulfate (SO42-): ≤0.02%
cation traces	Fe: ≤0.001%
	heavy metals (as Pb): ≤0.002%
storage temp.	2-8°C
SMILES string	OC(=O)C(Cl)(Cl)Cl
InChI	1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChI key	YNJBWRMUSHSURL-UHFFFAOYSA-N

Application

• Trichloroacetic acid has been used for the precipitation of sLRP (soluble circulating low density lipoprotein receptor-related protein-1) isolated from plasma.
• It has been used for the extraction of ascorbic acid from plant samples. It has also been used for the preparation of ascorbate standards for ascorbate assay.
• It has been used for the precipitation of IMAC (immobilized metal ion affinity chromatography)-isolated phosphoproteins.

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Safety Information

GHS05, GHS07, GHS09

Signal word Danger
Hazard statements H314-H335-H410
Precautionary statements P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RIDADR UN 1839 8 / PGII
WGK Germany 2
RTECS AJ7875000
Flash Point(F) >235.4 °F
Flash Point(C) >113 °C